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Florence is a home rule-class city  in Boone CountyKentuckyin the United States. Immediate and simple Endorsement. The climate is continental with a wide range of temperatures from winter to summer. Get Connected With a Lender. The city itself is located in the narrow, relatively steep-sided valley of the Ohio River. There are 9, households out of whichFlorence, Kentucky Add Favorite 4 Reviews | Review This Place. The area’s largest industry and employer is Procter & Gamble, with a history that dates back to the city’s early stockyards when soap. Florence, Kentucky From Wikipedia, the free encyclopedia. Florence is the closest significant town to Cincinnati/Northern Kentucky International Airport. Turfway Park Racetrack in Florence, Kentucky features a one mile track with live thoroughbred racing on Wednesday-Sunday starting at am with simulcasting year round.